Hprt1tm2(CAG-TBX2,-EGFP)Akis
Targeted Allele Detail
|
Symbol: |
Hprt1tm2(CAG-TBX2,-EGFP)Akis |
Name: |
hypoxanthine phosphoribosyltransferase 1; targeted mutation 2, Andreas Kispert |
MGI ID: |
MGI:5314539 |
Synonyms: |
HpCT2 |
Gene: |
Hprt1 Location: ChrX:52077014-52110536 bp, + strand Genetic Position: ChrX, 29.31 cM, cytoband A6
|
Alliance: |
Hprt1tm2(CAG-TBX2,-EGFP)Akis page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:181526
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
129
|
|
Allele Type: |
|
Targeted (Conditional ready, Humanized sequence, Inserted expressed sequence, Reporter) |
Mutations: |
|
Insertion, Intragenic deletion
|
|
|
Hprt1tm2(CAG-TBX2,-EGFP)Akis expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
TBX2 (6909) |
|
|
|
|
|
Mutation details: Exon 1 was replaced with a CAG promoter, loxP site, neo/stop cassette, loxP2272 site, inverted human TBX2 cDNA, IRES and EGFP cassette, loxP site, and loxP2272 site. Cre-mediated recombination is required to achieve expression of TBX2 and EGFP.
(J:181526)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Hprt1 Mutation: |
1279 strains or lines available
|
|
Original: |
J:181526 Singh R, et al., Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formation. Cell Mol Life Sci. 2012 Apr;69(8):1377-89 |
All: |
8 reference(s) |
|