Spata22^repro42
Chemically induced Allele Detail

Summary

• Symbol: Spata22^repro42
• Name: spermatogenesis associated 22; reproductive mutant 42, JAX Reproductive Mutagenesis Program
• MGI ID: MGI:5314540
• Synonyms: Spata22^Y275X
• Gene: Spata22 Location: Chr11:73220567-73236870 bp, + strand Genetic Position: Chr11, 45.29 cM
• Alliance: Spata22^repro42 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A transversion in exon 8 that results in the amino acid substitution of tyrosine to a premature stop codon at position 275 (Y275X). (J:182054, J:249350)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Spata22 Mutation: 31 strains or lines available

References

• Original: J:182054 La Salle S, et al., Spata22, a novel vertebrate-specific gene, is required for meiotic progress in mouse germ cells. Biol Reprod. 2012 Feb;86(2):45
• All: 3 reference(s)