Mir205^tm1Mtm
Targeted Allele Detail

Summary

• Symbol: Mir205^tm1Mtm
• Name: microRNA 205; targeted mutation 1, Michael McManus
• MGI ID: MGI:5314655
• Gene: Mir205 Location: Chr1:193189771-193189838 bp, - strand Genetic Position: Chr1, 97.82 cM
• Alliance: Mir205^tm1Mtm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181752
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Conditional ready, Null/knockout, Reporter) Mutation: Insertion Mutation details: A targeting vector was designed to insert an FRT site followed by a lacZ gene, a loxP site, a neomycin cassette, an FRT site and a loxP site (FRT-lacZ-loxP-Neo-FRT-loxP) upstream of the microRNA stem loop and one loxP site immediately downstream of the microRNA stem loop. (J:181752)

Generation of the Mir205^tm1Mtm, Mir205^tm1.1Mtm, and Mir205^tm1.2Mtm alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mir205 Mutation: 3 strains or lines available

References

• Original: J:181752 Park CY, et al., A resource for the conditional ablation of microRNAs in the mouse. Cell Rep. 2012;1(4):385-91
• All: 7 reference(s)