Rassf2^tm1Dlim
Targeted Allele Detail

Summary

• Symbol: Rassf2^tm1Dlim
• Name: Ras association (RalGDS/AF-6) domain family member 2; targeted mutation 1, Dae-Sik Lim
• MGI ID: MGI:5314787
• Gene: Rassf2 Location: Chr2:131834770-131872336 bp, - strand Genetic Position: Chr2, 64.14 cM
• Alliance: Rassf2^tm1Dlim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181952
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A puro cassette replaced exons 4 and 5. Western blot analysis confirmed the absence of protein expression in the liver, brain, lung, bone marrow, lymph node, spleen and testis. (J:181952)

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rassf2 Mutation: 25 strains or lines available

References

• Original: J:181952 Song H, et al., Ablation of Rassf2 induces bone defects and subsequent haematopoietic anomalies in mice. EMBO J. 2012 Mar 7;31(5):1147-59
• All: 1 reference(s)