Gpr21^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gpr21^tm1Dgen
• Name: G protein-coupled receptor 21; targeted mutation 1, Deltagen
• MGI ID: MGI:5314799
• Gene: Gpr21 Location: Chr2:37406638-37409293 bp, + strand Genetic Position: Chr2, 24.19 cM
• Alliance: Gpr21^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181127
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• A lacZ/neo cassette replaced exon 1. (J:181127)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr21 Mutation: 19 strains or lines available

References

• Original: J:181127 Gardner J, et al., G-protein-coupled receptor GPR21 knockout mice display improved glucose tolerance and increased insulin response. Biochem Biophys Res Commun. 2012 Feb 3;418(1):1-5
• All: 2 reference(s)