Aicda^tm1(cre)Njen
Targeted Allele Detail

Summary

• Symbol: Aicda^tm1(cre)Njen
• Name: activation-induced cytidine deaminase; targeted mutation 1, Nancy A Jenkins
• MGI ID: MGI:5314932
• Synonyms: Aicda^Cre
• Gene: Aicda Location: Chr6:122530768-122541139 bp, + strand Genetic Position: Chr6, 57.65 cM, cytoband F2
• Alliance: Aicda^tm1(cre)Njen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181782
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Aicda^tm1(cre)Njen expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Aicda (MGI:1342279)

• Mutation details: The cDNA encoding cre recombinase was inserted into Aicda between the stop codon and the 3' untranslated region. Details will be published elsewhere. (J:181782)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Aicda (mouse) Summary of all recombinase alleles driven by Aicda. Alliance mouse Aicda gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aicda Mutation: 57 strains or lines available

References

• Original: J:181782 Xu S, et al., The RNase III enzyme Dicer is essential for germinal center B-cell formation. Blood. 2012 Jan 19;119(3):767-76
• All: 2 reference(s)