Mir187^tm1.1Mtm
Targeted Allele Detail

Summary

• Symbol: Mir187^tm1.1Mtm
• Name: microRNA 187; targeted mutation 1.1, Michael McManus
• MGI ID: MGI:5314975
• Gene: Mir187 Location: Chr18:24562167-24562227 bp, - strand Genetic Position: Chr18, 13.17 cM
• Alliance: Mir187^tm1.1Mtm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181832
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed the neo cassette and the microRNA stem loop from Mir187^tm1Mtm. qRT-PCR analysis confirmed the loss of the microRNA. (J:181752)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir187 Mutation: 5 strains or lines available

References

• Original: J:181832 Garner AR, et al., Generation of a synthetic memory trace. Science. 2012 Mar 23;335(6075):1513-6
• All: 3 reference(s)