Wnt7a^px-2J
Chemically induced Allele Detail

Summary

• Symbol: Wnt7a^px-2J
• Name: wingless-type MMTV integration site family, member 7A; postaxial hemimelia 2 Jackson
• MGI ID: MGI:5315309
• Gene: Wnt7a Location: Chr6:91340963-91388335 bp, - strand Genetic Position: Chr6, 40.45 cM
• Alliance: Wnt7a^px-2J page

Mutation origin

• Strain of Origin: C3HeB/FeJ or C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A single G to T transversion in exon 4 is predicted to change amino acid residue 304 from cysteine to phenylalanine. (J:188478)
• Inheritance: Recessive

Disease models

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Wnt7a Mutation: 26 strains or lines available

References

• Original: J:188478 Harris BS, et al., Postaxial hemimelia 2 Jackson: a new point mutation in Wnt7a and model of Fuhrmann syndrome. MGI Direct Data Submission. 2012
• All: 1 reference(s)