Arl6ip5^tm1Tnkk
Targeted Allele Detail

Summary

• Symbol: Arl6ip5^tm1Tnkk
• Name: ADP-ribosylation factor-like 6 interacting protein 5; targeted mutation 1, Toshio Nakaki
• MGI ID: MGI:5315599
• Gene: Arl6ip5 Location: Chr6:97187753-97210276 bp, + strand Genetic Position: Chr6, 44.91 cM, cytoband D3
• Alliance: Arl6ip5^tm1Tnkk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182338
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced most of exon 1. Western blot analysis confirmed the absence of protein expression in brain extracts. (J:182338)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Arl6ip5 Mutation: 16 strains or lines available

References

• Original: J:182338 Aoyama K, et al., Increased neuronal glutathione and neuroprotection in GTRAP3-18-deficient mice. Neurobiol Dis. 2012 Mar;45(3):973-82
• All: 2 reference(s)