Catsperd^tm1.1Clph
Targeted Allele Detail

Summary

• Symbol: Catsperd^tm1.1Clph
• Name: cation channel sperm associated auxiliary subunit delta; targeted mutation 1.1, David E Clapham
• MGI ID: MGI:5315769
• Synonyms: CATSPERdelta^-
• Gene: Catsperd Location: Chr17:56935143-56971456 bp, + strand Genetic Position: Chr17, 29.43 cM
• Alliance: Catsperd^tm1.1Clph page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182472
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: One loxP site was inserted in intron 8 and a neomycin cassette followed by a second loxP site was inserted in intron 9. Exon 9 and the neo selection cassette were subsequently removed by transient cre expression. (J:182472)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Catsperd Mutation: 50 strains or lines available

References

• Original: J:182472 Chung JJ, et al., A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa. Nat Commun. 2011 Jan 11;2:153
• All: 6 reference(s)