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Catsperdtm1.1Clph
Targeted Allele Detail
Summary
Symbol: Catsperdtm1.1Clph
Name: cation channel sperm associated auxiliary subunit delta; targeted mutation 1.1, David E Clapham
MGI ID: MGI:5315769
Synonyms: CATSPERdelta-
Gene: Catsperd  Location: Chr17:56935143-56971456 bp, + strand  Genetic Position: Chr17, 29.43 cM
Alliance: Catsperdtm1.1Clph page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:182472
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsOne loxP site was inserted in intron 8 and a neomycin cassette followed by a second loxP site was inserted in intron 9. Exon 9 and the neo selection cassette were subsequently removed by transient cre expression. (J:182472)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Catsperd Mutation:  50 strains or lines available
References
Original:  J:182472 Chung JJ, et al., A novel gene required for male fertility and functional CATSPER channel formation in spermatozoa. Nat Commun. 2011 Jan 11;2:153
All:  6 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory