Cbln2^tm1Jim
Targeted Allele Detail

Summary

• Symbol: Cbln2^tm1Jim
• Name: cerebellin 2 precursor protein; targeted mutation 1, James I Morgan
• MGI ID: MGI:5316017
• Gene: Cbln2 Location: Chr18:86729235-86736408 bp, + strand Genetic Position: Chr18, 58.63 cM
• Alliance: Cbln2^tm1Jim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182277
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 through 3 were replaced with a neomycin resistance cassette. qRT-PCR confirmed the absence of mRNA. (J:182277)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cbln2 Mutation: 16 strains or lines available

References

• Original: J:182277 Rong Y, et al., Comparison of Cbln1 and Cbln2 functions using transgenic and knockout mice. J Neurochem. 2012 Feb;120(4):528-40
• All: 2 reference(s)