T(7;19)145H
Radiation induced Allele Detail

Summary

• Symbol: T(7;19)145H
• Name: reciprocal translocation, Chr 7 and 19, Harwell 145
• MGI ID: MGI:5316041
• Synonyms: T145H
• Gene: T(7;19)145H Location: unknown Genetic Position: Chr19, cytoband D1

Mutation origin

• Strain of Origin: (C3H/HeH x 101/H)F1

Mutation description

• Allele Type: Radiation induced
• Mutation: Translocation
• Mutation details: This reciprocal translocation was found by fertility screening of progeny of male mice exposed to 600 rad X-rays to the hind part of the body and mated immediately afterward, during the pre-sterile period. Analysis of giemsa- (G-) banded chromosomes placed the cytological breakpoints at bands 7B3 and 19D1. The genetic breakpoints were determined by duplication-deletion mapping to lie between Gpi1 and Oca2 on Chr 7 and between Papss2 and Hps6 on Chr 19. (J:5959, J:34742)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any T(7;19)145H Mutation: 1 strain or line available

References

• Original: J:34742 Lyon MF, et al., Autosomal translocations causing male sterility and viable aneuploidy in the mouse. Cytogenetics. 1966;5:335-54
• All: 3 reference(s)