Yap1^tm1.1Fcam
Targeted Allele Detail

Summary

• Symbol: Yap1^tm1.1Fcam
• Name: yes-associated protein 1; targeted mutation 1.1, Fernando D Camargo
• MGI ID: MGI:5316446
• Synonyms: Yap1^flox
• Gene: Yap1 Location: Chr9:7932000-8004597 bp, - strand Genetic Position: Chr9, 2.46 cM
• Alliance: Yap1^tm1.1Fcam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:171057
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of exon 2. Flp-mediated recombination removed the neo cassette and left exon 1 and 2 floxed. (J:171057)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Yap1 Mutation: 38 strains or lines available

References

• Original: J:171057 Schlegelmilch K, et al., Yap1 acts downstream of alpha-catenin to control epidermal proliferation. Cell. 2011 Mar 4;144(5):782-95
• All: 31 reference(s)