Ackr4^tm1Ccbl
Targeted Allele Detail

Summary

• Symbol: Ackr4^tm1Ccbl
• Name: atypical chemokine receptor 4; targeted mutation 1, Conrad C Bleul
• MGI ID: MGI:5316751
• Synonyms: CCX-CKR1-EGFP, Ccx-ckr^eGFP, EGFP^CCX-CKR1
• Gene: Ackr4 Location: Chr9:103974881-104003842 bp, - strand Genetic Position: Chr9, 56.47 cM
• Alliance: Ackr4^tm1Ccbl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182799
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion The N-terminal half the single coding exon (exon 4) was replaced with an EGFP and neo. (J:182799)

Generation of the Ackr4^tm1Ccbl allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ackr4 Mutation: 25 strains or lines available

References

• Original: J:182799 Heinzel K, et al., A silent chemokine receptor regulates steady-state leukocyte homing in vivo. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8421-6
• All: 17 reference(s)