Maf^tm2.1Cbm
Targeted Allele Detail

Summary

• Symbol: Maf^tm2.1Cbm
• Name: MAF bZIP transcription factor; targeted mutation 2.1, Carmen Birchmeier
• MGI ID: MGI:5316775
• Synonyms: c-Maf^flox
• Gene: Maf Location: Chr8:116429992-116433633 bp, - strand Genetic Position: Chr8, 62.61 cM
• Alliance: Maf^tm2.1Cbm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181639
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of the coding region. An FRT-flanked neo cassette with a 5' loxP site was inserted downstream of the open reading frame. Flp-mediated recombination removed the neo cassette. (J:181639)

Expression

In Mice Carrying this Mutation:	3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Maf Mutation: 27 strains or lines available

References

• Original: J:181639 Wende H, et al., The transcription factor c-Maf controls touch receptor development and function. Science. 2012 Mar 16;335(6074):1373-6
• All: 27 reference(s)