Ffar4^tm1Gdds
Targeted Allele Detail

Summary

• Symbol: Ffar4^tm1Gdds
• Name: free fatty acid receptor 4; targeted mutation 1, Gozoh Tsujimoto
• MGI ID: MGI:5316909
• Gene: Ffar4 Location: Chr19:38085527-38102711 bp, + strand Genetic Position: Chr19, 32.73 cM
• Alliance: Ffar4^tm1Gdds page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182599
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A neo cassette replaced exon 1. RT-PCR confirmed the absence of transcript expression in lung, stomach, small intestine, colon and adipose tissue (epididymal, subcutaneous, peri-renal and brown). (J:182599)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar4 Mutation: 25 strains or lines available

References

• Original: J:182599 Ichimura A, et al., Dysfunction of lipid sensor GPR120 leads to obesity in both mouse and human. Nature. 2012 Mar 15;483(7389):350-4
• All: 7 reference(s)