Tg(Rfx2-cre)1Bknr
Transgene Detail

Summary

• Symbol: Tg(Rfx2-cre)1Bknr
• Name: transgene insertion 1, Martina Brueckner
• MGI ID: MGI:5317178
• Synonyms: Rfx2-Cre
• Transgene: Tg(Rfx2-cre)1Bknr Location: unknown
• Alliance: Tg(Rfx2-cre)1Bknr page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Rfx2-cre)1Bknr expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Rfx2

• Mutation details: A BAC (280 kb) containing the Rfx2 gene was modified by insertion of cre recombinase in-frame immediately after the translational start codon in exon 2. The transgenic construct was used to generate 2 founder mice. One line demonstrated the expected expression pattern and was studied in greater detail. (J:182770)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Rfx2 (species not specified) Summary of all recombinase alleles driven by Rfx2.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:182770 Bisgrove BW, et al., RFX2 is essential in the ciliated organ of asymmetry and an RFX2 transgene identifies a population of ciliated cells sufficient for fluid flow. Dev Biol. 2012 Mar 1;363(1):166-78
• All: 1 reference(s)