Mir22^tm1.1Arod
Targeted Allele Detail

Summary

• Symbol: Mir22^tm1.1Arod
• Name: microRNA 22; targeted mutation 1.1, Antony Rodriguez
• MGI ID: MGI:5317341
• Gene: Mir22 Location: Chr11:75354542-75354636 bp, + strand Genetic Position: Chr11, 45.91 cM
• Alliance: Mir22^tm1.1Arod page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183005
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A targeting vector containing a loxP flanked PGK-EM7-NeobpA cassette was used to disrupt Mir22 (microRNA 22). Cre-mediated recombination removed the neo cassette. No gene product (mRNA) is detected by qPCR analysis of heart tissue. (J:183005)

Expression

In Mice Carrying this Mutation:	3 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Mir22 Mutation: 6 strains or lines available

References

• Original: J:183005 Rodriguez A, Direct Data Submission 2012/05/07. MGI Direct Data Submission. 2012
• All: 11 reference(s)