Hmgn2^tm1.1Mbus
Targeted Allele Detail

Summary

• Symbol: Hmgn2^tm1.1Mbus
• Name: high mobility group nucleosomal binding domain 2; targeted mutation 1.1, Michael Bustin
• MGI ID: MGI:5317455
• Synonyms: Hmgn2^tm1Mbus
• Gene: Hmgn2 Location: Chr4:133692050-133695302 bp, - strand Genetic Position: Chr4, 66.47 cM
• Alliance: Hmgn2^tm1.1Mbus page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182874
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• Mutation details: The targeting vector contains loxP site inserted upstream of exon 1 and a FRT-flanked NEO cassette followed by a second loxP site downstream of exon 6. Cre-mediated recombination removed the neo cassette and exons 1-6. (J:241631)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hmgn2 Mutation: 13 strains or lines available

References

• Original: J:182874 Rochman M, et al., Effects of HMGN variants on the cellular transcription profile. Nucleic Acids Res. 2011 May;39(10):4076-87
• All: 7 reference(s)