Tg(Igh*-Mir125b-1)5Toki
Transgene Detail

Summary

• Symbol: Tg(Igh*-Mir125b-1)5Toki
• Name: transgene insertion 5, Toshio Kitamura
• MGI ID: MGI:5317552
• Synonyms: Emu/miR-125b-TG
• Transgene: Tg(Igh*-Mir125b-1)5Toki Location: unknown
• Alliance: Tg(Igh*-Mir125b-1)5Toki page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Igh*-Mir125b-1)5Toki expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir125b-1 (MGI:2676810)

• Mutation details: The human Emu enhancer with the Igh promoter drives late pro-B cell-specific expression of the mouse pre-microRNA inserted into the rabbit beta-globin gene. Two lines were generated (5 and 116). Line 116 contains more copies of the transgene compared with line 5. (J:178816)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:178816 Enomoto Y, et al., Emu/miR-125b transgenic mice develop lethal B-cell malignancies. Leukemia. 2011 Dec;25(12):1849-56
• All: 2 reference(s)