Tg(CAG-Mir21,-EGFP)#Eno
Transgene Detail

Summary

• Symbol: Tg(CAG-Mir21,-EGFP)#Eno
• Name: transgene insertion, Eric N Olson
• MGI ID: MGI:5317720
• Synonyms: CAG-miR-21-EGFP
• Transgene: Tg(CAG-Mir21,-EGFP)#Eno Location: unknown
• Alliance: Tg(CAG-Mir21,-EGFP)#Eno page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-Mir21,-EGFP)#Eno expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Mir21a (MGI:2676885)

• Mutation details: The CAG promoter drives ubiquitous expression of a floxed lacZ/STOP cassette followed by the mouse coding sequencem IRES and EGFP. Cre-mediated recombination removed the lacZ/STOP cassette and allows for the expression of the mouse cDNA and EGFP. Lines 1 and 2 were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:164198)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:164198 Hatley ME, et al., Modulation of K-Ras-dependent lung tumorigenesis by MicroRNA-21. Cancer Cell. 2010 Sep 14;18(3):282-93
• All: 2 reference(s)