Aven^tm1.1Zrng
Targeted Allele Detail

Summary

• Symbol: Aven^tm1.1Zrng
• Name: apoptosis, caspase activation inhibitor; targeted mutation 1.1, Martin Zoernig
• MGI ID: MGI:5317759
• Synonyms: Aven^tm(GFP)
• Gene: Aven Location: Chr2:112323231-112461598 bp, + strand Genetic Position: Chr2, 57.04 cM, cytoband E4
• Alliance: Aven^tm1.1Zrng page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The sequence within the first exon that encodes the first 200 amino acids of the protein has been replaced with a green fluorescent protein (GFP) cDNA that includes an ATG translation termination codon and a polyadenylation signal. GFP is therefore expressed under control of the endogenous promoter, and the endogenous protein is not expressed. A tk-neo cassette that was flanked by loxP sites in the original construct was deleted in vivo. (J:82809)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Aven Mutation: 41 strains or lines available

References

• Original: J:82809 European Mouse Mutant Archive, Information obtained from the European Mouse Mutant Archive (EMMA). Unpublished. 2003-2013
• All: 1 reference(s)