Pknox1tm1.2Xzh
Targeted Allele Detail
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Symbol: |
Pknox1tm1.2Xzh |
Name: |
Pbx/knotted 1 homeobox; targeted mutation 1.2, Xin Zhang |
MGI ID: |
MGI:5317869 |
Synonyms: |
Prep1delta |
Gene: |
Pknox1 Location: Chr17:31783708-31826667 bp, + strand Genetic Position: Chr17, 16.78 cM, cytoband B-C
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Alliance: |
Pknox1tm1.2Xzh page
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Germline Transmission: |
Earliest citation of germline transmission:
J:182769
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 8 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 8 via homologous recombination. Recombinase mediated recombination removed the neo cassette and exon 8. Western blot analysis detected the presence of a truncated protein.
(J:182769)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Pknox1 Mutation: |
90 strains or lines available
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Original: |
J:182769 Carbe C, et al., The functional role of the Meis/Prep-binding elements in Pax6 locus during pancreas and eye development. Dev Biol. 2012 Mar 1;363(1):320-9 |
All: |
1 reference(s) |
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