Nrarp^tm1Ybes
Targeted Allele Detail

Summary

• Symbol: Nrarp^tm1Ybes
• Name: Notch-regulated ankyrin repeat protein; targeted mutation 1, Yasumasa Bessho
• MGI ID: MGI:5317888
• Gene: Nrarp Location: Chr2:25070770-25073351 bp, + strand Genetic Position: Chr2, 17.05 cM
• Alliance: Nrarp^tm1Ybes page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183027
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The coding sequence was replaced with an IRES-lacZ and neo cassette. In situ hydridization confirmed the absence of transcript expression in E10.5 embryos. (J:183027)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrarp Mutation: 8 strains or lines available

References

• Original: J:183027 Kim W, et al., The period of the somite segmentation clock is sensitive to Notch activity. Mol Biol Cell. 2011 Sep;22(18):3541-9
• All: 1 reference(s)