Tg(Col11a2-SIK3)#Ntsu
Transgene Detail

Summary

• Symbol: Tg(Col11a2-SIK3)#Ntsu
• Name: transgene insertion, Noriyuki Tsumaki
• MGI ID: MGI:5317919
• Synonyms: Col11a2-hSIK3
• Transgene: Tg(Col11a2-SIK3)#Ntsu Location: unknown
• Alliance: Tg(Col11a2-SIK3)#Ntsu page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Col11a2-SIK3)#Ntsu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  SIK3 (23387)

  Sik3	(MGI:2446296)

• Mutation details: The mouse promoter drives expression of the human cDNA in chondrocytes. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:182752)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:182752 Sasagawa S, et al., SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice. Development. 2012 Mar;139(6):1153-63
• All: 1 reference(s)