Il13ra1^tm1Zagh
Targeted Allele Detail

Summary

• Symbol: Il13ra1^tm1Zagh
• Name: interleukin 13 receptor, alpha 1; targeted mutation 1, Habib Zaghouani
• MGI ID: MGI:5317952
• Synonyms: IL-13Ralpha1^-, IL-13Ralpha1-Neo^Rdeltaex7-9
• Gene: Il13ra1 Location: ChrX:35375763-35434912 bp, + strand Genetic Position: ChrX, 20.49 cM
• Alliance: Il13ra1^tm1Zagh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183111
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 7 through 9 were replaced with a neo cassette. Western blot analysis confirms the absence of protein expression in thymic cells. (J:183111)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 4 strains available Cell Lines: 0 lines available
• Carrying any Il13ra1 Mutation: 19 strains or lines available

References

• Original: J:183111 Haymaker CL, et al., Bone marrow-derived IL-13Ralpha1-positive thymic progenitors are restricted to the myeloid lineage. J Immunol. 2012 Apr 1;188(7):3208-16
• All: 10 reference(s)