Pald1^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Pald1^tm1Vlcg
• Name: phosphatase domain containing, paladin 1; targeted mutation 1, Velocigene
• MGI ID: MGI:5317962
• Synonyms: Paladin^LacZ, Pald1^-
• Gene: Pald1 Location: Chr10:61155435-61219309 bp, - strand Genetic Position: Chr10, 32.19 cM, cytoband B4
• Alliance: Pald1^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181634
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ and floxed neo cassette replaced exons 1 through 18. Western blot analysis confirmed the absence of protein expression in the lungs. (J:181634)

Expression

In Mice Carrying this Mutation:	119 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pald1 Mutation: 40 strains or lines available

References

• Original: J:181634 Wallgard E, et al., Paladin (X99384) is expressed in the vasculature and shifts from endothelial to vascular smooth muscle cells during mouse development. Dev Dyn. 2012 Apr;241(4):770-86
• All: 3 reference(s)