Gt(ROSA)26Sor^tm1(sb13)Tuv
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm1(sb13)Tuv
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, David A Tuveson
• MGI ID: MGI:5318064
• Synonyms: LSL-SB, Rosa26-LSL-SB13
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm1(sb13)Tuv page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:177503
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A construct, in which a floxed STOP cassette prevents expression of sleeping beauty 13 (sb13), was inserted into the locus. (J:177503)

Tumor Data

List all tumor models in MMHCdb carrying Gt(ROSA)26Sor^tm1(sb13)Tuv

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:177503 Karreth FA, et al., In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma. Cell. 2011 Oct 14;147(2):382-95
• All: 3 reference(s)