Tg(Aicda-cre)1Rcas
Transgene Detail

Summary

• Symbol: Tg(Aicda-cre)1Rcas
• Name: transgene insertion 1, Rafael Casellas
• MGI ID: MGI:5318074
• Synonyms: AID-Cre
• Transgene: Tg(Aicda-cre)1Rcas Location: unknown
• Alliance: Tg(Aicda-cre)1Rcas page

Transgene origin

• Strain of Origin: FVB/NCrl

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Aicda-cre)1Rcas expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Aicda

• Mutation details: The RPCI24-6817 bacterial artificial chromosome (BAC) was modified by introduction of a cre-recombinase gene within the first exon of the activation-induced cytidine deaminase (Aicda) gene. This 190 kb BAC transgene contains the modified AID-Cre gene, as well as Dpp3, Gdf3, Apobec, and Mfap5. This transgene was microinjected into the pronuclei of fertilized FVB/NCrl oocytes. A single founder was used to establish the line. (J:125740)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Aicda (species not specified) Summary of all recombinase alleles driven by Aicda. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:125740 Crouch EE, et al., Regulation of AID expression in the immune response. J Exp Med. 2007 May 14;204(5):1145-56
• All: 10 reference(s)