Tg(Aicda/EGFP)1Rcas
Transgene Detail

Summary

• Symbol: Tg(Aicda/EGFP)1Rcas
• Name: transgene insertion 1, Rafael Casellas
• MGI ID: MGI:5318088
• Synonyms: AID-GFP
• Transgene: Tg(Aicda/EGFP)1Rcas Location: unknown
• Alliance: Tg(Aicda/EGFP)1Rcas page

Transgene origin

• Strain of Origin: C57BL/6NCrl

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: The RPCI24-6817 bacterial artificial chromosome (BAC) was modified by targeting the enhanced green fluorescent protein (EGFP) fusion protein gene in frame into exon 5 of the activation-induced cytidine deaminase (Aicda) locus. The 190 kb BAC transgene contains the modified AID-GFP gene, as well as Dpp3, Gdf3, Apobec1, and Mfap5 genes. Line 1 was generated. (J:125740)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:125740 Crouch EE, et al., Regulation of AID expression in the immune response. J Exp Med. 2007 May 14;204(5):1145-56
• All: 20 reference(s)