Ppard^tm1Yjj
Targeted Allele Detail

Summary

• Symbol: Ppard^tm1Yjj
• Name: peroxisome proliferator activator receptor delta; targeted mutation 1, Yan J Jiang
• MGI ID: MGI:5318332
• Synonyms: PPARdelta^ki
• Gene: Ppard Location: Chr17:28451715-28520446 bp, + strand Genetic Position: Chr17, 14.64 cM
• Alliance: Ppard^tm1Yjj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182124
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exon 4 was replaced with a beta-galactosidase gene. (J:182124)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppard Mutation: 68 strains or lines available

References

• Original: J:182124 Jiang YJ, et al., PPARdelta activation promotes stratum corneum formation and epidermal permeability barrier development during late gestation. J Invest Dermatol. 2010 Feb;130(2):511-9
• All: 1 reference(s)