Slamf6^tm1Pls
Targeted Allele Detail

Summary

• Symbol: Slamf6^tm1Pls
• Name: SLAM family member 6; targeted mutation 1, Pamela L Schwartzberg
• MGI ID: MGI:5318529
• Synonyms: Ly108^-
• Gene: Slamf6 Location: Chr1:171745002-171776525 bp, + strand Genetic Position: Chr1, 79.54 cM
• Alliance: Slamf6^tm1Pls page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183088
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A stop codon was introduced into exon 2 and replaced part of exons 2 and 3 with a neo cassette. Flow cytometry confirmed the absence of protein expression. (J:183088, J:193308)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Slamf6 Mutation: 33 strains or lines available

Notes

ES cell line = HGTC-8 (C57BL/6J)

References

• Original: J:183088 Dutta M, et al., Characterization of Ly108 in the thymus: evidence for distinct properties of a novel form of Ly108. J Immunol. 2012 Apr 1;188(7):3031-41
• All: 5 reference(s)