Capn1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Capn1^tm1Dgen
• Name: calpain 1; targeted mutation 1, Deltagen
• MGI ID: MGI:5319092
• Gene: Capn1 Location: Chr19:6038573-6065855 bp, - strand Genetic Position: Chr19, 4.34 cM
• Alliance: Capn1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183585
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• A lacZ-neo cassette was inserted into the gene. (J:183585)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Capn1 Mutation: 33 strains or lines available

References

• Original: J:183585 Scalia R, et al., A novel role for calpain in the endothelial dysfunction induced by activation of angiotensin II type 1 receptor signaling. Circ Res. 2011 Apr 29;108(9):1102-11
• All: 2 reference(s)