Stat1^tm1.2Mmul
Targeted Allele Detail

Summary

• Symbol: Stat1^tm1.2Mmul
• Name: signal transducer and activator of transcription 1; targeted mutation 1.2, Mathias Muller
• MGI ID: MGI:5319175
• Synonyms: Stat1^delta
• Gene: Stat1 Location: Chr1:52158599-52201024 bp, + strand Genetic Position: Chr1, 26.81 cM
• Alliance: Stat1^tm1.2Mmul page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183580
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exons 6 through 10 and the neo cassette. Western blot analysis confirmed the absence of protein expression in the liver, lung and spleen. (J:183580)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stat1 Mutation: 74 strains or lines available

References

• Original: J:183580 Wallner B, et al., Generation of mice with a conditional Stat1 null allele. Transgenic Res. 2012 Feb;21(1):217-24
• All: 2 reference(s)