Mtss1^tm1Pla
Targeted Allele Detail

Summary

• Symbol: Mtss1^tm1Pla
• Name: MTSS I-BAR domain containing 1; targeted mutation 1, Pekka Lappalainen
• MGI ID: MGI:5319219
• Gene: Mtss1 Location: Chr15:58813083-58953854 bp, - strand Genetic Position: Chr15, 25.09 cM
• Alliance: Mtss1^tm1Pla page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182970
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A transposon-based method was used to insert a neo cassette into exon 1. Western bot analysis confirmed the absence of protein expression. (J:182970)

Expression

In Mice Carrying this Mutation:	17 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtss1 Mutation: 120 strains or lines available

References

• Original: J:182970 Saarikangas J, et al., Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia. J Cell Sci. 2011 Apr 15;124(Pt 8):1245-55
• All: 4 reference(s)