Nipsnap1^tm1Eoa
Targeted Allele Detail

Summary

• Symbol: Nipsnap1^tm1Eoa
• Name: nipsnap homolog 1; targeted mutation 1, Emiko Okuda-Ashitaka
• MGI ID: MGI:5319314
• Gene: Nipsnap1 Location: Chr11:4823951-4844200 bp, + strand Genetic Position: Chr11, 3.07 cM
• Alliance: Nipsnap1^tm1Eoa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183272
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: A floxed neo cassette replaced exons 2, 3 and 4. Western blot analysis confirmed the absence of protein expression in the brain, spinal cord, liver and kidneys. (J:183272)

Generation of the Nipsnap1^tm1Eoa allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nipsnap1 Mutation: 30 strains or lines available

References

• Original: J:183272 Okuda-Ashitaka E, et al., Identification of NIPSNAP1 as a nocistatin-interacting protein involving pain transmission. J Biol Chem. 2012 Mar 23;287(13):10403-13
• All: 1 reference(s)