Birc2^tm1.1Rbr
Targeted Allele Detail

Summary

• Symbol: Birc2^tm1.1Rbr
• Name: baculoviral IAP repeat-containing 2; targeted mutation 1.1, Robert Brink
• MGI ID: MGI:5319370
• Gene: Birc2 Location: Chr9:7818228-7837065 bp, - strand Genetic Position: Chr9, 2.46 cM, cytoband A1
• Alliance: Birc2^tm1.1Rbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182515
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exon 1 and the hygro cassette. (J:182515)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Birc2 Mutation: 33 strains or lines available

References

• Original: J:182515 Moulin M, et al., IAPs limit activation of RIP kinases by TNF receptor 1 during development. EMBO J. 2012;31(7):1679-91
• All: 5 reference(s)