Nme3^tm1Bgh
Targeted Allele Detail

Summary

• Symbol: Nme3^tm1Bgh
• Name: NME/NM23 nucleoside diphosphate kinase 3; targeted mutation 1, Bernhard G Herrmann
• MGI ID: MGI:5319393
• Synonyms: Nme3^tm5Bgh
• Gene: Nme3 Location: Chr17:25115474-25116496 bp, + strand Genetic Position: Chr17, 12.53 cM
• Alliance: Nme3^tm1Bgh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:183481
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neo STOP cassette replaced exon 1 and part of exon 2. RT-PCR confirmed the absence of transcript expression. (J:183481)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nme3 Mutation: 10 strains or lines available

References

• Original: J:183481 Bauer H, et al., The nucleoside diphosphate kinase gene Nme3 acts as quantitative trait locus promoting non-Mendelian inheritance. PLoS Genet. 2012 Mar;8(3):e1002567
• All: 1 reference(s)