Tg(Kap-Ppara/AGT)562Dpo
Transgene Detail
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| Symbol: |
Tg(Kap-Ppara/AGT)562Dpo |
| Name: |
transgene insertion 562, Didier Portilla |
| MGI ID: |
MGI:5319689 |
| Synonyms: |
Kap2-Ppara |
| Transgene: |
Tg(Kap-Ppara/AGT)562Dpo Location: unknown
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| Alliance: |
Tg(Kap-Ppara/AGT)562Dpo page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inducible, Inserted expressed sequence) |
| Inducer: |
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androgen |
| Mutation: |
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Insertion
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Mutation details: A 1542 bp fragment of the Kap promoter drives expression of a FLAG-tagged Ppara gene and exons 3-5 and 3' untranslated region of the human angiotensin gene. Three lines were generated (560, 561, 562). This line had the highest level of transgene expression in the kidney. Testosterone treatment induces higher levels of transgene expression in the kidneys of female mice.
(J:172337)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:172337 Li S, et al., Transgenic expression of proximal tubule peroxisome proliferator-activated receptor-alpha in mice confers protection during acute kidney injury. Kidney Int. 2009 Nov;76(10):1049-62 |
| All: |
3 reference(s) |
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Analysis Tools
