Inhbe/Inhbc^tm1Sjl
Targeted Allele Detail

Summary

• Symbol: Inhbe/Inhbc^tm1Sjl
• Name: inhibin beta-E; targeted mutation 1, Sejin Lee
• MGI ID: MGI:5319698
• Gene: Inhbe Location: Chr10:127185271-127187717 bp, - strand Genetic Position: Chr10, 74.5 cM
• Alliance: Inhbe/Inhbc^tm1Sjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:182827
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intergenic deletion
• Mutation details: The exon encoding the C terminal domain of Inhbe and all of the coding sequence of Inhbc were replaced with a neo cassette via homologous recombination. (J:182827)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Inhbe Mutation: 12 strains or lines available

References

• Original: J:182827 Lee SJ, et al., Regulation of muscle mass by follistatin and activins. Mol Endocrinol. 2010 Oct;24(10):1998-2008
• All: 1 reference(s)