Inhbb^tm1Grid
Targeted Allele Detail

Summary

• Symbol: Inhbb^tm1Grid
• Name: inhibin beta-B; targeted mutation 1, Tom Gridley
• MGI ID: MGI:5319783
• Synonyms: BetaB^delta1
• Gene: Inhbb Location: Chr1:119343195-119349978 bp, - strand Genetic Position: Chr1, 52.29 cM
• Alliance: Inhbb^tm1Grid page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:19647
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 1.3 kb genomic fragment encompassing about 60% (69 of 115 amino acids) of the coding sequence was replaced with a neo cassette via homologous recombination. (J:19647)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Inhbb Mutation: 24 strains or lines available

References

• Original: J:19647 Schrewe H, et al., Mice homozygous for a null mutation of activin beta B are viable and fertile. Mech Dev. 1994 Jul;47(1):43-51
• All: 1 reference(s)