Ppp2ca^tm1.2Nju
Targeted Allele Detail

Summary

• Symbol: Ppp2ca^tm1.2Nju
• Name: protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform; targeted mutation 1.2, Model Animal Research Center of Nanjing University
• MGI ID: MGI:5320588
• Synonyms: Ppp2ca^delta
• Gene: Ppp2ca Location: Chr11:51989651-52013576 bp, + strand Genetic Position: Chr11, 31.86 cM
• Alliance: Ppp2ca^tm1.2Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184036
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre-mediated recombination removed exons 3, 4 and 5. (J:184036)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp2ca Mutation: 25 strains or lines available

References

• Original: J:184036 Gu P, et al., Generation of Ppp2Ca and Ppp2Cb conditional null alleles in mouse. Genesis. 2012 May;50(5):429-36
• All: 1 reference(s)