Ppp2cb^tm1.1Nju
Targeted Allele Detail

Summary

• Symbol: Ppp2cb^tm1.1Nju
• Name: protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; targeted mutation 1.1, Model Animal Research Center of Nanjing University
• MGI ID: MGI:5320589
• Synonyms: Ppp2cb^delta
• Gene: Ppp2cb Location: Chr8:34089653-34109469 bp, + strand Genetic Position: Chr8, 20.63 cM
• Alliance: Ppp2cb^tm1.1Nju page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184036
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre-mediated recombination removed exon 3 and the neo cassette. The absence of transcript expression in the heart was confirmed. (J:184036)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp2cb Mutation: 21 strains or lines available

References

• Original: J:184036 Gu P, et al., Generation of Ppp2Ca and Ppp2Cb conditional null alleles in mouse. Genesis. 2012 May;50(5):429-36
• All: 1 reference(s)