Bcl11a^tm1.1Sbri
Targeted Allele Detail

Summary

• Symbol: Bcl11a^tm1.1Sbri
• Name: BCL11 transcription factor A; targeted mutation 1.1, Stefan Britsch
• MGI ID: MGI:5320881
• Gene: Bcl11a Location: Chr11:24028056-24124123 bp, + strand Genetic Position: Chr11, 14.41 cM
• Alliance: Bcl11a^tm1.1Sbri page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184011
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A floxed neo cassette was inserted 3' of exon 1 and a loxP site was inserted 5' of exon 1 via homologous recombination. Cre mediated recombination exon 1. Protein expression was not detected in homozygous embryos. (J:184011)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcl11a Mutation: 44 strains or lines available

References

• Original: J:184011 John A, et al., Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41
• All: 1 reference(s)