Asgr1^Mhdabap005
Chemically induced Allele Detail

Summary

• Symbol: Asgr1^Mhdabap005
• Name: asialoglycoprotein receptor 1; Martin Hrabe de Angelis bone alkaline phospatase mutant 005
• MGI ID: MGI:5424890
• Synonyms: Asgr1^BAP005, bone alkaline phospatase mutant 005
• Gene: Asgr1 Location: Chr11:69944911-69948720 bp, + strand Genetic Position: Chr11, 42.98 cM
• Alliance: Asgr1^Mhdabap005 page

Mutation origin

• Strain of Origin: C3HeB/FeJ

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: This ENU-induced mutation was isolated in a screen for metabolic bone disease as part of the Munich ENU Mutagenesis Project. An A-to-G point mutation at position 815 of the cDNA is predicted to alter codon 272 in the encoded protein from a tyrosine to a cysteine residue. (J:183993)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Asgr1 Mutation: 16 strains or lines available

References

• Original: J:183993 Sabrautzki S, et al., New mouse models for metabolic bone diseases generated by genome-wide ENU mutagenesis. Mamm Genome. 2012 Aug;23(7-8):416-30
• All: 1 reference(s)