Vps41^tm1.1Ywd
Targeted Allele Detail

Summary

• Symbol: Vps41^tm1.1Ywd
• Name: VPS41 HOPS complex subunit; targeted mutation 1.1, Yoh Wada
• MGI ID: MGI:5425109
• Synonyms: mVam2^-
• Gene: Vps41 Location: Chr13:18901462-19050981 bp, + strand Genetic Position: Chr13, 6.75 cM
• Alliance: Vps41^tm1.1Ywd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184591
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted in intron 18 and an FRT-loxP flanked neomycin cassette was inserted upstream of exon 15. Flp recombinase excised the selection caqssette leaving exons 15 to 18 flanked by loxP sites. Expression of cre recombinase then removed expns 15-18. (J:184591, J:184592)

Expression

In Mice Carrying this Mutation:	57 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Vps41 Mutation: 47 strains or lines available

References

• Original: J:184592 Aoyama M, et al., Simple and straightforward construction of a mouse gene targeting vector using in vitro transposition reactions. Nucleic Acids Res. 2005;33(5):e52
• All: 2 reference(s)