Celf4^tm1.2Frk
Targeted Allele Detail

Summary

• Symbol: Celf4^tm1.2Frk
• Name: CUGBP, Elav-like family member 4; targeted mutation 1.2, Wayne N Frankel
• MGI ID: MGI:5425630
• Synonyms: Celf4^null
• Gene: Celf4 Location: Chr18:25610689-25887214 bp, - strand Genetic Position: Chr18, 13.92 cM, cytoband B1
• Alliance: Celf4^tm1.2Frk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:181678
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 1 was deleted in the germline by cre-mediated recombination of loxP sites that flanked exon 1. Immunoblot analysis of hippocampus and cerebral cortex indicate that no detectable protein is expressed from this allele in homozygous mice. (J:181678)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Celf4 Mutation: 27 strains or lines available

References

• Original: J:181678 Wagnon JL, et al., Etiology of a genetically complex seizure disorder in Celf4 mutant mice. Genes Brain Behav. 2011 Oct;10(7):765-77
• All: 3 reference(s)