Fgf18^tm1Tri
Targeted Allele Detail

Summary

• Symbol: Fgf18^tm1Tri
• Name: fibroblast growth factor 18; targeted mutation 1, Toru Imamura
• MGI ID: MGI:5425911
• Synonyms: Fgf18^flox
• Gene: Fgf18 Location: Chr11:33067430-33097400 bp, - strand Genetic Position: Chr11, 19.21 cM
• Alliance: Fgf18^tm1Tri page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184628
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neo cassette with a 5' loxP site was inserted upstream of exon 3. An additional loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the neo cassette. (J:184628)

Expression

In Mice Carrying this Mutation:

2 assay results 1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Fgf18 Mutation: 10 strains or lines available

References

• Original: J:184628 Kimura-Ueki M, et al., Hair cycle resting phase is regulated by cyclic epithelial FGF18 signaling. J Invest Dermatol. 2012 May;132(5):1338-45
• All: 3 reference(s)