About   Help   FAQ
Smad7tm1.2Ink
Targeted Allele Detail
Summary
Symbol: Smad7tm1.2Ink
Name: SMAD family member 7; targeted mutation 1.2, Ingo Kleiter
MGI ID: MGI:5426021
Synonyms: Smad7delta
Gene: Smad7  Location: Chr18:75500600-75529006 bp, + strand  Genetic Position: Chr18, 51.06 cM, cytoband E2
Alliance: Smad7tm1.2Ink page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:184670
Parent Cell Line:  Bruce 4 (ES Cell)
Strain of Origin:  B6.Cg-Thy1a
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Cre mediated recombination of Smad7tm1.1 removed exon 1. (J:184670)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Smad7 Mutation:  53 strains or lines available
References
Original:  J:184670 Kleiter I, et al., Smad7 in T cells drives T helper 1 responses in multiple sclerosis and experimental autoimmune encephalomyelitis. Brain. 2010 Apr;133(Pt 4):1067-81
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory