Lfng^tm1.1Dihz
Targeted Allele Detail

Summary

• Symbol: Lfng^tm1.1Dihz
• Name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase; targeted mutation 1.1, David Ish-Horowicz
• MGI ID: MGI:5426216
• Synonyms: L10
• Gene: Lfng Location: Chr5:140593096-140601300 bp, + strand Genetic Position: Chr5, 79.15 cM
• Alliance: Lfng^tm1.1Dihz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:184024
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Humanized sequence)
• Mutation: Insertion
• Mutation details: A 10 kb intronic fragment from human DMD that is not expected to contain cis-regulatory elements active in the mouse presomitic mesoderm was inserted into the first intron. Cre-mediated recombination removed the floxed neo cassette inserted upstream of the human sequence. (J:184024)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lfng Mutation: 32 strains or lines available

References

• Original: J:184024 Stauber M, et al., Modifying transcript lengths of cycling mouse segmentation genes. Mech Dev. 2012 Mar;129(1-4):61-72
• All: 1 reference(s)